The 5th International R&D Dating will take place on October 24th in the “Carrousel du Louvre” right in the heart of Paris, on the theme of «Inflammation and inflammatory diseases». This topic, chosen by ARIIS and AVIESAN, is in agreement with the recommendation of the 5th meeting of the Strategic Council of Industries of Health (CSIS) held in January 2012.
Inflammation is part of a complex physiological process and plays a crucial role in the tissue response to harmful stimuli. However, acute or chronic inflammation can induce many diseases. Progress in the elucidation of the mechanisms that regulate inflammation and a reinforced organization of the patient treatment may allow a better medical care and the development of new anti-inflammatory drugs.
Inflammation is a worldwide priority for public health. In France, more than 80 research teams are working on inflammation and/or inflammatory diseases. These teams have made major progresses in the molecular and cellular bases of inflammation, as well as on clinical research, epidemiology, public health and translational research. Altogether, the results obtained result in a better understanding of inflammatory diseases.
The research developed in France is specifically focused on several aspects of inflammation and inflammatory diseases: elucidation of the cellular and molecular mechanisms that regulate inflammation; research on the interactions between components of the immune system during the inflammatory response and its chronicity; development of new experimental models of inflammatory pathologies and technological improvement to follow the onset and the evolution of the inflammatory response; role of the tissue environment and development of new cellular or molecular products targeting the pathways implicated in the early and late stages of the inflammatory response and inflammatory diseases without efficient therapies. Finally, genomic studies leads to the identification of molecular signatures that can be transferred to clinical studies and will allow better diagnosis, prognosis and improvement of treatments of inflammatory diseases.